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Best Vape Juice 2021
Last updated: July 29, 2021

Best Diacetyl-Free E-Juices 2021

E-juice brands with great-tasting diacetyl free e-liquids made with the best possible ingredients.
1st Place
Black Note Virginia Tobacco
Black Note

Black Note delivers a true premium tobacco experience — bold and robust tobacco flavors that are naturally-extracted from the finest-quality tobacco plants.

Kind Juice
Kind Juice

Are you looking for diacetyl-free e-juice? There is a lot of vape juice that claims to be a lot of things. Organic, vegan, cruelty-free, non-GMO… the list goes on. How do you know which ones are being honest? The best companies post lab results and certifications to back up their claims.

Never sacrifice flavor for safety! All of the products below have been tested and verified for quality. See the test results and learn more about diacetyl free e-juice in the guide below. If you want to jump right into it, here are the top seven best-tasting diacetyl-free e-juices available right now.

Black Note Virginia Tobacco

Black Note

Black Note provides premium e-juice for the true tobacco connoisseur. They’re all made with real tobacco using a natural extraction process. The flavors are robust, authentic and diacetyl-free. There’s also a variety of menthol flavors made with natural peppermint oil extract. Each flavor comes in a 50/50 VG/PG blend.

VaporFi Catch Ya Latte


VaporFi is on a mission to change smoker’s lives. All of their e-juice is made in the USA using kosher grade diacetyl-free ingredients. Choose from their dozens of finely crafted flavors or create your own personalized blends. There’s also three VG/PG levels to choose from: 50%, 70% and max VG.

Kind Juice

Kind Juice

Kind Juice provides a departure from your typical boring e-juice. They use natural extracts and organic ingredients with no artificial sweeteners or diacetyl. It’s some of the most unique e-liquid available. Their range spans from tobacco to floral and fruit nectar flavors. Each one is formulated with max VG.

Kais Virgin Vapor

KAI's Virgin Vapor

KAI’s Virgin Vapor might be clean as it gets. They perform testing to ensure diacetyl-free e-juice with state of the art GC-MS testing. They also use USP and kosher-grade ingredients and third-party organic flavorings. There’s a whole spectrum of flavors to choose and all of their e-juice contains maximum VG content.

Cosmic Fog

Cosmic Fog

Cosmic Fog has some of the most unique flavors out there. Thoroughly tested and crafted by vapers who have a background in culinary arts. All of them are made in an ISO 8 laboratory and are free of diacetyl and other contaminants. Each flavor provides a completely new experience for your taste buds.

Why vape diacetyl-free e-juice?

Diacetyl, called DA for short, is a naturally occurring compound found in the fermentation of beer. It’s also synthesized and used as a flavoring agent in food products for its rich mouthfeel and buttery taste. The scare over it has to do with it being the likely culprit in eight cases of popcorn lung, a deadly and irreversible lung disease that affected popcorn factory workers during the 1990s.

DA is safe to consume in foods, but it poses risks for inhalation. The popcorn factory workers were repeatedly exposed to industrial-sized vats of the chemical mixed with hot oil, which is far from the trace amounts found in any e-juice. But even if the risks are minor in comparison, many vapers want to avoid it.

Why aren’t all e-juices diacetyl-free?

After a 2014 study conducted by Dr. Farsalinos showed many e-juices on the market contained detectable amounts of DA, the hunt for diacetyl-free e-juice was on. The tricky part was finding them. Many of those companies in the study claimed their products were diacetyl-free, though the liquids in fact did test positive for it in Dr. Farsalinos’s study. Were they all lying?

As it turns out, the likelihood that any e-juice maker was (is) directly using DA as an ingredient is slim to none. It resides in some of the flavorings used to make the e-juice. In the earlier days of vaping, little was known about this fact. E-liquid manufacturers knew they weren’t adding some flavoring called diacetyl, but what they didn’t know was that it was hiding in plain sight. The only way now to be certain if an e-juice is DA-free is by having it independently tested by a third-party source like Enthalpy Labs. Many companies like the ones listed on this page in fact have these test results.

But not all vapers are concerned. For one, DA and its related chemicals called diketones add a rich flavor to e-juice that many vapers enjoy. Secondly, because DA is also one of the thousands of chemicals in cigarettes, and at levels 100 times higher (or more) than in e-juice, some vapers are willing to take the risk. If you were or are a smoker, you’ve already inhaled it – and a lot of it! Many vapers view the risks of DA in vaping as reduced harm since its content in cigarettes is so much more extreme.

Is diacetyl-free the safest e-liquid to vape?

The most suspect aspects of vape juice have to do with the inhalation of the vape flavorings. Eliminating any non-essential elements from e-juice will in fact make it safer. But if you want the absolute safest e-juice, you’re best off using unflavored. If unflavored vape juice doesn’t appeal to you, vaping diacetyl-free e-juice is at the very least a safer option than e-juice with it. But if your only other option is smoking, it almost doesn’t matter what you vape. Vaping is the safer choice and is at least 95% safer than smoking.

Test results for brands on this page

Vaping360 assumes no liability for claims from e-juice companies. All objective information on this page was provided to us directly from the manufacturer or the company’s website. Contact the manufacturer for more information on their ingredients, manufacturing processes, testing procedures, and test results.

Black Note
Kind Juice
KAI’s Virgin Vapor
Cosmic Fog

Best Beginner Vapes in 2021
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